Fetal programming of Parkinson’s and Alzheimer’s diseases: the role of epigenetic factors

In this paper, the main epigenetic factors involved in shaping the brain’s physical structure during development will be reviewed, with special emphasis on those related to Parkinson’s disease and Alzheimer’s disease in adulthood. These factors are: preterm delivery, maternal diet, trace metals, intrauterine infection, maternal stress, drugs, alcohol. Epigenetics may allow a novel therapeutic and preventive approach for neurodegeneration.


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